Publications 2018

Publications - 2018

SSPC, the Science Foundation Ireland (SFI) Research Centre for Pharmaceuticals

  1. Albadarin, A. B., Solomon, S., Abou Daher, M., & Walker, G. (2018). Efficient removal of anionic and cationic dyes from aqueous systems using spent Yerba Mate “Ilex paraguariensis”. Journal of the Taiwan Institute of Chemical Engineers, 82, 144-155. doi: 10.1016/j.jtice.2017.11.012 
  2. Asghar, M. A., Zahir, E., Shahid, S. M., Khan, M. N., Iqbal, J., & Walker, G. (2018). Iron, copper and silver nanoparticles: Green synthesis using green and black tea leaves extracts and evaluation of antibacterial, antifungal and aflatoxin B-1 adsorption activity. Lwt-Food Science and Technology, 90, 98-107. doi:10.1016/j.lwt.2017.12.009
  3. Ashour, R. M., Samouhos, M., Legaria, E. P., Svard, M., Hogblom, J., Forsberg, K., Rasmuson, A. C. (2018). DTPA-Functionalized Silica Nano- and Microparticles for Adsorption and Chromatographic Separation of Rare Earth Elements. Acs Sustainable Chemistry & Engineering, 6(5), 6889-6900. doi:10.1021/acssuschemeng.8b00725[P4][P5][P7]
  4. Baghel, S., Cathcart, H., & O’Reilly, N. J. (2018a). Investigation into the Solid-State Properties and Dissolution Profile of Spray-Dried Ternary Amorphous Solid Dispersions: A Rational Step toward the Design and Development of a Multicomponent Amorphous System. Molecular Pharmaceutics, 15(9), 3796-3812. doi:10.1021/acs.molpharmaceut.8b00306 [T8]
  5. Baghel, S., Cathcart, H., & O’Reilly, N. J. (2018b). Understanding the generation and maintenance of supersaturation during the dissolution of amorphous solid dispersions using modulated DSC and H-1 NMR. International Journal of Pharmaceutics, 536(1), 414-425. doi:10.1016/j.ijpharm.2017.11.056 [T8]
  6. Bannigan, P., Durack, E., Mathur, H., Rea, M. C., Ross, R. P., & Hudson, S. P. (2018). Delivery of a hydrophobic drug into the lower gastrointestinal system via an endogenous enzyme-mediated carrier mechanism: An in vitro study. European Journal of Pharmaceutics and Biopharmaceutics, 133, 12-19. doi:10.1016/j.ejpb.2018.09.019 [P4][P6]
  7. Bannigan, P., Stokes, K., Kumar, A., Madden, C., & Hudson, S. P. (2018). Investigating the effects of amphipathic gastrointestinal compounds on the solution behaviour of salt and free base forms of clofazimine: An in vitro evaluation. International Journal of Pharmaceutics, 552(1-2), 180-192. doi:10.1016/j.ijpharm.2018.09.012 [P4][P6]
  8. Blackshields, C. A., & Crean, A. M. (2018). Continuous powder feeding for pharmaceutical solid dosage form manufacture: a short review. Pharmaceutical Development and Technology, 23(6), 554-560. doi:10.1080/10837450.2017.1339197 [P6][P8][P9]
  9. Bree, G., Coughlan, C., Geaney, H., & Ryan, K. M. (2018). Investigation into the Selenization Mechanisms of Wurtzite CZTS Nanorods. Acs Applied Materials & Interfaces, 10(8), 7117-7125. doi:10.1021/acsarn.7b18711[LT2]
  10. Bree, G., Geaney, H., & Ryan, K. M. (2018). Common Battery Anode Testing Protocols Are Not Suitable for New Combined Alloying and Conversion Materials. Chemelectrochem, 5(23), 3757-3763. doi:10.1002/celc.201800990[LT2]
  11. Bree, G., Geaney, H., Stokes, K., & Ryan, K. M. (2018). Aligned Copper Zinc Tin Sulfide Nanorods as Lithium-Ion Battery Anodes with High Specific Capacities. Journal of Physical Chemistry C, 122(35), 20090-20098. doi:10.1021/acs.jpcc.8b05386[LT2]
  12. Budova, M., Skorepova, E., & Cejka, J. (2018). Sodium Aspirin Salts: Crystallization and Characterization. Crystal Growth & Design, 18(9), 5287-5294. doi:10.1021/acs.cgd.8b00718 [T4]
  13. Bueno, R. A., Crowley, C. M., Davern, P., Hodnett, B. K., & Hudson, S. (2018). Heterogeneous Crystallization of Fenofibrate onto Pharmaceutical Excipients. Crystal Growth & Design, 18(4), 2151-2164. doi:10.1021/acs.cgd.7b01598 [P6]
  14. Buzid, A., McGlacken, G. P., Glennon, J. D., & Luong, J. H. T. (2018). Electrochemical Sensing of Biotin Using Nafion-Modified Boron-Doped Diamond Electrode. Acs Omega, 3(7), 7776-7782. doi:10.1021/acsomega.8b01209 [T3]
  15. Buzid, A., Luong, J. H. T., Reen, F. J., O’Gara, F., Glennon, J. D., & McGlacken, G. P. (2018). Rapid Electrochemical Detection of Pseudomonas aeruginosa Signaling Molecules by Boron-Doped Diamond Electrode. Methods Mol Biol, 1673, 107-116. doi:10.1007/978-1-4939-7309-5_9 [T3]
  16. Cano, R., Mackey, K., & McGlacken, G. P. (2018). Recent advances in manganese-catalysed C-H activation: scope and mechanism. Catalysis Science & Technology, 8(5), 1251-1266. doi:10.1039/c7cy02514a [T3]
  17. Carucci, C., Bruen, L., Gascon, V., Paradisi, F., & Magner, E. (2018). Significant Enhancement of Structural Stability of the Hyperhalophilic ADH from Haloferax volcanii via Entrapment on Metal Organic Framework Support. Langmuir, 34(28), 8274-8280. doi:10.1021/acs.langmuir.8b01037 [P2][T1]
  18. Casamayou-Boucau, Y., & Ryder, A. G. (2018). Accurate anisotropy recovery from fluorophore mixtures using Multivariate Curve Resolution (MCR). Analytica Chimica Acta, 1000, 132-143. doi:10.1016/j.aca.2017.11.031 [T5]
  19. Cassidy, J., & Paradisi, F. (2018). Haloquadratum walsbyi Yields a Versatile, NAD(+)/NADP(+) Dual Affinity, Thermostable, Alcohol Dehydrogenase (HwADH). Molecular Biotechnology, 60(6), 420-426. doi:10.1007/s12033-018-0083-6 [P2]
  20. Castilla, I. A., Woods, D. F., Reen, F. J., & O’Gara, F. (2018). Harnessing Marine Biocatalytic Reservoirs for Green Chemistry Applications through Metagenomic Technologies. Marine Drugs, 16(7), 21. doi:10.3390/md16070227 [P2]
  21. Claveau, R., Twamley, B., & Connon, S. J. (2018). Dynamic kinetic resolution of bis-aryl succinic anhydrides: enantioselective synthesis of densely functionalised gamma-butyrolactones. Chemical Communications, 54(26), 3231-3234. doi:10.1039/c8cc00609a [P2]
  22. Contente, M. L., & Paradisi, F. (2018). Self-sustaining closed-loop multienzyme-mediated conversion of amines into alcohols in continuous reactions. Nature Catalysis, 1(6), 452-459. doi:10.1038/s41929-018-0082-9 [P2]
  23. Craig, R., Sorrentino, E., & Connon, S. J. (2018). Enantioselective Alkylation of 2-Oxindoles Catalyzed by a Bifunctional Phase-Transfer Catalyst: Synthesis of (-)-DebromoflustramineB. Chemistry-a European Journal, 24(18), 4528-4531. doi:10.1002/chem.201800313 [P2]
  24. Crowley, D. C., Lynch, D., & Maguire, A. R. (2018). Copper-Mediated, Heterogeneous, Enantioselective Intramolecular Buchner Reactions of alpha-Diazoketones Using Continuous Flow Processing. Journal of Organic Chemistry, 83(7), 3794-3805. doi:10.1021/acs.joc.8b00147 [P1][P2][P3]
  25. Darwish, S., Zeglinski, J., Krishna, G. R., Shaikh, R., Khraisheh, M., Walker, G. M., & Croker, D. M. (2018). A New 1:1 Drug-Drug Cocrystal of Theophylline and Aspirin: Discovery, Characterization, and Construction of Ternary Phase Diagrams. Crystal Growth & Design, 18(12), 7526-7532. doi:10.1021/acs.cgd.8b01330 [P5]
  26. Davis, M., & Walker, G. (2018). Recent strategies in spray drying for the enhanced bioavailability of poorly water-soluble drugs. Journal of Controlled Release, 269, 110-127. doi:10.1016/j.jconrel.2017.11.005 [P8][P9][T8]
  27. Davis, M. T., Potter, C. B., & Walker, G. M. (2018). Downstream processing of a ternary amorphous solid dispersion: The impacts of spray drying and hot melt extrusion on powder flow, compression and dissolution. International Journal of Pharmaceutics, 544(1), 242-253. doi:10.1016/j.ijpharm.2018.04.038 [P8][P9] [T8]
  28. de Souza, B., Keshavarz, L., Steendam, R. R. E., Dennehy, O. C., Lynch, D., Collins, S. G., . . . Frawley, P. J. (2018). Solubility Measurement and Thermodynamic Modeling of N-(4-Methylphenyl-Z-3-chloro-2-(phenylthio)propenamide in 12 Pure Solvents at Temperatures Ranging from 278.15 to 318.15 K. Journal of Chemical and Engineering Data, 63(5), 1419-1428. doi:10.1021/acs.jced.7b01011 [LT1][P7]
  29. do Amaral, L. H., do Carmo, F. A., Amaro, M. I., de Sousa, V. P., da Silva, L., de Almeida, G. S., . . . Cabral, L. M. (2018). Development and Characterization of Dapsone Cocrystal Prepared by Scalable Production Methods. Aaps Pharmscitech, 19(6), 2687-2699. doi:10.1208/s12249-018-1101-5 [P8]
  30. Foley, A. M., Gavin, D. P., Deasy, R. E., Milner, S. E., Moody, T. S., Eccles, K. S., . . . Maguire, A. R. (2018). Dynamic kinetic resolution of 2-methyl-2-nitrocyclohexanol: Combining the intramolecular nitroaldol (Henry) reaction & lipase-catalysed resolution. Tetrahedron, 74(13), 1435-1443. doi:10.1016/j.tet.2018.01.055 [P1][P2][P3][T1]
  31. Foley, S., Geaney, H., Bree, G., Mukherjee, S., Zaworotko, M. J., & Ryan, K. M. (2018). Layered Bimetallic Metal-Organic Material Derived Cu2SnS3/SnS2/C Composite for Anode Applications in Lithium-Ion Batteries. Chemelectrochem, 5(23), 3764-3770. doi:10.1002/celc.201800989 [LT2]
  32. Foley, S., Geaney, H., Bree, G., Stokes, K., Connolly, S., Zaworotko, M. J., & Ryan, K. M. (2018). Copper Sulfide (CuxS) Nanowire-in-Carbon Composites Formed from Direct Sulfurization of the Metal-Organic Framework HKUST-1 and Their Use as Li-Ion Battery Cathodes. Advanced Functional Materials, 28(19), 8. doi:10.1002/adfm.201800587 [LT2]
  33. Gao, Y., Glennon, B., Kamaraju, V. K., Hou, G. Y., & Donnellan, P. (2018). Dissolution Kinetics of a BCS Class II Active Pharmaceutical Ingredient. Organic Process Research & Development, 22(3), 328-336. doi:10.1021/acs.oprd.7b00365[P4][P5]
  34. Gervasi, V., Agnol, R. D., Cullen, S., McCoy, T., Vucen, S., & Crean, A. (2018). Parenteral protein formulations: An overview of approved products within the European Union. European Journal of Pharmaceutics and Biopharmaceutics, 131, 8-24. doi:10.1016/j.ejpb.2018.07.011 [P8][P9][T7]
  35. Heffernan, C., Ukrainczyk, M., Zeglinski, J., Hodnett, B. K., & Rasmuson, A. C. (2018). Influence of Structurally Related Impurities on the Crystal Nucleation of Curcumin. Crystal Growth & Design, 18(8), 4715-4723. doi:10.1021/acs.cgd.8b00692 [P4][P5][P7][T5]
  36. Hurley, D., Potter, C. B., Walker, G. M., & Higginbotham, C. L. (2018). Investigation of Ethylene Oxide-co-propylene Oxide for Dissolution Enhancement of Hot-Melt Extruded Solid Dispersions. Journal of Pharmaceutical Sciences, 107(5), 1372-1382. doi:10.1016/j.xphs.2018.01.016 [P9]
  37. Inkielewicz-Stepniak, I., Tajber, L., Behan, G., Zhang, H. Z., Radomski, M. W., Medina, C., & Santos-Martinez, M. J. (2018). The Role of Mucin in the Toxicological Impact of Polystyrene Nanoparticles. Materials, 11(5), 12. doi:10.3390/ma11050724[P6][P8][P9]
  38. James, J., Akula, R., & Guiry, P. J. (2018). Pd-Catalyzed Decarboxylative Asymmetric Protonation of Sterically Hindered -Aryl Lactones and Dihydrocoumarins. Advanced Synthesis & Catalysis, 360(16), 3138-3149. doi:10.1002/adsc.201800724[P1]
  39. Jones, D. J., Khandavilli, U. B. R., O’Leary, E. M., Lawrence, S. E., & O’Sullivan, T. P. (2018). Efficient S-Acylation of Thiourea. Synopen, 2(4), 263-267. doi:10.1055/s-0037-1610370 [P5]
  40. Kamali, N., O’Malley, C., Mahon, M. F., Erxleben, A., & McArdle, P. (2018). Use of Sublimation Catalysis and Polycrystalline Powder Templates for Polymorph Control of Gas Phase Crystallization. Crystal Growth & Design, 18(6), 3510-3516. doi:10.1021/acs.cgd.8b00268 [P6]
  41. Karimi-Jafari, M., Padrela, L., Walker, G. M., & Croker, D. M. (2018). Creating Cocrystals: A Review of Pharmaceutical Cocrystal Preparation Routes and Applications. Crystal Growth & Design, 18(10), 6370-6387. doi:10.1021/acs.cgd.8b00933 [P5]
  42. Kavanagh, O. N., Albadarin, A. B., Croker, D. M., Healy, A. M., & Walker, G. M. (2018). Maximising success in multidrug formulation development: A review. Journal of Controlled Release, 283, 1-19. doi:10.1016/j.jconrel.2018.05.024 [P8][P9]
  43. Kavanagh, O. N., Croker, D. M., Walker, G. M., & Zaworotko, M. J. (2019). Pharmaceutical cocrystals: from serendipity to design to application. Drug Discov Today, 24(3), 796-804. doi:10.1016/j.drudis.2018.11.023 [T4]
  44. Kelleher, J. F., Gilvary, G. C., Madi, A. M., Jones, D. S., Li, S., Tian, Y., . . . Healy, A. M. (2018). A comparative study between hot-melt extrusion and spray-drying for the manufacture of anti-hypertension compatible monolithic fixed-dose combination products. International Journal of Pharmaceutics, 545(1-2), 183-196. doi:10.1016/j.ijpharm.2018.05.008 [P8][P9]
  45. Kent, C., Khandavilli, U. B. R., Alfarsi, A., Hanna-Brown, M., McSweeney, S., Kruse, J., . . . Fitzpatrick, D. (2018). Tracking Cocrystallization of Active Pharmaceutical Ingredients with Benzoic Acid Coformer Using Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS). Crystal Growth & Design, 18(11), 6528-6537. doi:10.1021/acs.cgd.8b00668 [T7]
  46. Keshayarz, L., Steendam, R. R. E., & Frawley, P. J. (2018). Impact of Mother Liquor Recycle on the Impurity Buildup in Crystallization Processes. Organic Process Research & Development, 22(11), 1541-1547. doi:10.1021/acs.oprd.8b00308[P7]
  47. Khandavilli, U. B. R., Gavin, D. P., Maguire, A. R., Nolan, M., & Lawrence, S. E. (2018). Exploring the Crystal Landscape of 3-Methyl-2-phenylbutyramide: Crystallization of Metastable Racemic Forms from the Stable Conglomerate. Crystal Growth & Design, 18(6), 3549-3557. doi:10.1021/acs.cgd.8b00348[T4][P5]
  48. Khandavilli, U. B. R., Skorepova, E., Sinha, A. S., Bhogala, B. R., Maguire, N. M., Maguire, A. R., & Lawrence, S. E. (2018). Cocrystals and a Salt of the Bioactive Flavonoid: Naringenin. Crystal Growth & Design, 18(8), 4571-4577. doi:10.1021/acs.cgd.8b00557 [T4][P5]
  49. Knapik-Kowalczuk, J., Wojnarowska, Z., Chmiel, K., Rams-Baron, M., Tajber, L., & Paluch, M. (2018). Can Storage Time Improve the Physical Stability of Amorphous Pharmaceuticals with Tautomerization Ability Exposed to Compression? The Case of a Chloramphenicol Drug. Molecular Pharmaceutics, 15(5), 1928-1940. doi:10.1021/acs.molpharmaceut.8b00099 [P9]
  50. Kollamaram, G., Croker, D. M., Walker, G. M., Goyanes, A., Basit, A. W., & Gaisford, S. (2018). Low temperature fused deposition modeling (FDM) 3D printing of thermolabile drugs. International Journal of Pharmaceutics, 545(1-2), 144-152. doi:10.1016/j.ijpharm.2018.04.055 [P8][P9]
  51. Kollamaram, G., Faucher, A., Croker, D. M., & Walker, G. M. (2018). Valvejet Technology for the Production of a Personalised Fixed Dose Combination of Ramipril and Glimepiride: an Investigative Study on the Stability of Ramipril. Pharmaceutical Research, 35(9), 15. doi:10.1007/s11095-018-2465-7 [P8][P9]
  52. Kollamaram, G., Hopkins, S. C., Glowacki, B. A., Croker, D. M., & Walker, G. M. (2018). Inkjet printing of paracetamol and indomethacin using electromagnetic technology: Rheological compatibility and polymorphic selectivity. European Journal of Pharmaceutical Sciences, 115, 248-257. doi:10.1016/j.ejps.2018.01.036 [P8][P9]
  53. Korkmaz, K., Alemrajabi, M., Rasmuson, A., & Forsberg, K. (2018). Recoveries of Valuable Metals from Spent Nickel Metal Hydride Vehicle Batteries via Sulfation, Selective Roasting, and Water Leaching. Journal of Sustainable Metallurgy, 4(3), 313-325. doi:10.1007/s40831-018-0169-1[P4][P5][P7]
  54. Kozyra, A., Mugheirbi, N. A., Paluch, K. J., Garbacz, G., & Tajber, L. (2018). Phase Diagrams of Polymer-Dispersed Liquid Crystal Systems of Itraconazole/Component Immiscibility Induced by Molecular Anisotropy. Molecular Pharmaceutics, 15(11), 5192-5206. doi:10.1021/acs.molpharmaceut.8b00724[P8]
  55. Krishna, G. R., Ukrainczyk, M., Zeglinski, J., & Rasmuson, A. C. (2018). Prediction of Solid State Properties of Cocrystals Using Artificial Neural Network Modeling. Crystal Growth & Design, 18(1), 133-144. doi:10.1021/acs.cgd.7b00966 [T4] [P4][P5][P7]
  56. Kumar, D., Worku, Z. A., Gao, Y., Kamaraju, V. K., Glennon, B., Babu, R. P., & Healy, A. M. (2018). Comparison of wet milling and dry milling routes for ibuprofen pharmaceutical crystals and their impact on pharmaceutical and biopharmaceutical properties. Powder Technology, 330, 228-238. doi:10.1016/j.powtec.2018.02.022 [LT2][P8][P9]
  57. Kurniawan, T. A., Lin, Y. Y., Tong, O., Albadarin, A. B., & Walker, G. (2018). BaTiO3/TiO2 composite-assisted photocatalytic degradation for removal of acetaminophen from synthetic wastewater under UV-vis irradiation. Materials Science in Semiconductor Processing, 73, 42-50. doi:10.1016/j.mssp.2017.06.048 [P8][P9]
  58. Lamy, B., Tewes, F., Serrano, D. R., Lamarche, I., Gobin, P., Couet, W., . . . Marchand, S. (2018). New aerosol formulation to control ciprofloxacin pulmonary concentration. Journal of Controlled Release, 271, 118-126. doi:10.1016/j.jconrel.2017.12.021[P8]
  59. Leane, M., Pitt, K., Reynolds, G. K., Dawson, N., Ziegler, I., Szepes, A., . . . Grp, M. C. S. W. (2018). Manufacturing classification system in the real world: factors influencing manufacturing process choices for filed commercial oral solid dosage formulations, case studies from industry and considerations for continuous processing. Pharmaceutical Development and Technology, 23(10), 964-977. doi:10.1080/10837450.2018.1534863 [T7]
  60. Lin, Y. Y., Kurniawan, T. A., Albadarin, A. B., & Walker, G. (2018). Enhanced removal of acetaminophen from synthetic wastewater using multi-walled carbon nanotubes (MWCNTs) chemically modified with NaOH, HNO3/H2SO4, ozone, and/or chitosan. Journal of Molecular Liquids, 251, 369-377. doi:10.1016/j.molliq.2017.12.051[P8][P9]
  61. Looije, N., Gillissen, J. J. J., Sundaresan, S., & Van den Akker, H. E. A. (2018). Introducing a variable speed of sound in single-component lattice Boltzmann simulations of isothermal fluid flows. Computers & Fluids, 167, 129-145. doi:10.1016/j.compfluid.2018.02.037 [MOMEnTUM]
  62. Lynch, A., Jia, L. J., Svard, M., & Rasmuson, A. C. (2018). Crystal Growth of Salicylamide in Organic Solvents. Crystal Growth & Design, 18(12), 7305-7315. doi:10.1021/acs.cgd.8b00767 [P4][P5]
  63. Lynch, M. B., Lawrence, S. E., & Nolan, M. (2018). Predicting Nucleation of Isonicotinamide from the Solvent-Solute Interactions of Isonicotinamide in Common Organic Solvents. Journal of Physical Chemistry A, 122(12), 3301-3312. doi:10.1021/acs.jpca.8b01342 [P5]
  64. Maguire, N. M., Ford, A., Balzarini, J., & Maguire, A. R. (2018). Synthesis of Guanine alpha-Carboxy Nucleoside Phosphonate (G-alpha-CNP), a Direct Inhibitor of Multiple Viral DNA Polymerases. Journal of Organic Chemistry, 83(17), 10510-10517. doi:10.1021/acs.joc.8b01124 [P1][P2][P3]
  65. Maher, A., Hodnett, B. K., Coughlan, N., O’Brien, M., & Croker, D. M. (2018). Application of New Technology to a Mature Piroxicam Crystallization Process To Gain Process Understanding and Control, via Industrial-Academic Collaboration. Organic Process Research & Development, 22(3), 306-311. doi:10.1021/acs.oprd.7b00347 [P5]
  66. Marques, C. S., Lawrence, S. E., & Burke, A. J. (2018). Pd-Catalyzed One-Pot Borylation/Intramolecular Asymmetric Arylation on alpha-Ketiminoamides: Innovative Approach to Chiral 3-Amino-2-oxindoles. Synlett, 29(4), 497-502. doi:10.1055/s-0036-1590940 [T4][P5]
  67. Martinez, J., Varela, R. R., Forsberg, K., & Rasmuson, A. (2018). Factors influencing separation selectivity of rare earth elements in flat sheet supported liquid membranes. Chemical Engineering Science, 191, 134-155. doi:10.1016/j.ces.2018.06.018 [P4][P5][P7]
  68. McCarthy, C. A., Ahern, R. J., Devine, K. J., & Crean, A. M. (2018). Role of Drug Adsorption onto the Silica Surface in Drug Release from Mesoporous Silica Systems. Molecular Pharmaceutics, 15(1), 141-149. doi:10.1021/acs.molpharmaceut.7b00778 [P6][P8][P9]
  69. McComiskey, K. P. M., Mugheirbi, N. A., Stapleton, J., & Tajber, L. (2018). In situ monitoring of nanoparticle formation: Antisolvent precipitation of azole anti-fungal drugs. International Journal of Pharmaceutics, 543(1-2), 201-213. doi:10.1016/j.ijpharm.2018.03.054[LT2]
  70. McComiskey, K. P. M., & Tajber, L. (2018). Comparison of particle size methodology and assessment of nanoparticle tracking analysis (NTA) as a tool for live monitoring of crystallisation pathways. European Journal of Pharmaceutics and Biopharmaceutics, 130, 314-326. doi:10.1016/j.ejpb.2018.07.012 [LT2][P6][P8][P9]
  71. McGlacken, G. P., Hayes, S., Maguire, A. R., O’Halloran, J., & Hodnett, K. (2018). Industry-Academia Partnership: The Synthesis and Solid-State Pharmaceutical Centre (SSPC) as a Collaborative Approach from Molecule to Medicine. Chemistry-a European Journal, 24(2), 499-503. doi:10.1002/chem.201704326 [T3]
  72. Mc Gillicuddy, A., Crean, A. M., Kelly, M., & Sahm, L. J. (2018). Oral medicine modifications to meet the needs of older adults: The views of community-dwelling older adults and their carers. Pharmacoepidemiology and Drug Safety, 27, 10-11.[P6][P8][P9]
  73. Melnikau, D., Elcoroaristizabal, S., & Ryder, A. G. (2018). An excitation emission fluorescence lifetime spectrometer using a frequency doubled supercontinuum laser source. Methods and Applications in Fluorescence, 6(4), 12. doi:10.1088/2050-6120/aad9ae [T5]
  74. Moynihan, H. A., & Armstrong, D. (2018). Determination of composition distributions of multi-particle crystalline samples by sequential dissolution with concomitant particle sizing and solution analysis. Crystengcomm, 20(18), 2617-2633. doi:10.1039/c8ce00206a [T5]
  75. Muimhneachain, E. O., Reen, F. J., O’Gara, F., & McGlacken, G. P. (2018). Analogues of Pseudomonas aeruginosa signalling molecules to tackle infections. Organic & Biomolecular Chemistry, 16(2), 169-179. doi:10.1039/c7ob02395b [T3]
  76. Mukherjee, S., Zarghami, A., Haringa, C., van As, K., Kenjeres, S., & Van den Akker, H. E. A. (2018). Simulating liquid droplets: A quantitative assessment of lattice Boltzmann and Volume of Fluid methods. International Journal of Heat and Fluid Flow, 70, 59-78. doi:10.1016/j.ijheatfluidflow.2017.12.001 [MOMEnTUM]
  77. Mylonas-Margaritis, L., Winterlich, M., Efthymiou, C. G., Lazarides, T., McArdle, P., & Papatriantafyllopoulou, C. (2018). New insights into oximic ligands: Synthesis and characterization of 1D chains by the use of pyridine 2-amidoxime and polycarboxylates. Polyhedron, 151, 360-368. doi:10.1016/j.poly.2018.05.027 [P6]
  78. Padrela, L., Rodrigues, M. A., Duarte, A., Dias, A. M. A., Braga, M. E. M., & de Sousa, H. C. (2018). Supercritical carbon dioxide-based technologies for the production of drug nanoparticles/nanocrystals – A comprehensive review. Advanced Drug Delivery Reviews, 131, 22-78. doi:10.1016/j.addr.2018.07.010 [P6][LT2]
  79. Peddapatla, R. V. G., Ahmed, M. R., Blackshields, C. A., Sousa-Gallagher, M. J., McSweeney, S., Kruse, J., . . . Fitzpatrick, D. (2018). Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): A Novel Approach To Investigate the Wettability of Pharmaceutical Powder Blends. Molecular Pharmaceutics, 15(1), 31-39. doi:10.1021/acs.molpharmaceut.7b00658
  80. Persoons, T., Cressall, R., & Alimohammadi, S. (2018). Validating a Reduced-Order Model for Synthetic Jet Actuators Using CFD and Experimental Data. Actuators, 7(4), 17. doi:10.3390/act7040067 [T7]
  81. Pezzoli, R., Lyons, J. G., Gately, N., & Higginbotham, C. L. (2018). Investigation of miscibility estimation methods between indomethacin and poly(vinylpyrrolidone-co-vinyl acetate). International Journal of Pharmaceutics, 549(1-2), 50-57. doi:10.1016/j.ijpharm.2018.07.039 [P9]
  82. Pishnamazi, M., Casilagan, S., Clancy, C., Shirazian, S., Iqbal, J., Egan, D., . . . Collins, M. N. (2019). Microcrystalline cellulose, lactose and lignin blends: Process mapping of dry granulation via roll compaction. Powder Technology, 341, 38-50. doi:10.1016/j.powtec.2018.07.003 [Momentum Spoke]
  83. Pita, I. A., Kumbham, M., Schmidt, M., Gleeson, M., Ryan, K. M., Silien, C., & Liu, N. (2018). Surface plasmon propagation enhancement via bowtie antenna incorporation in Au- mica block waveguides. Applied Optics, 57(22), E50-E56. doi:10.1364/ao.57.000e50 [LT2]
  84. Pitzalis, F., Carucci, C., Naseri, M., Fotouhi, L., Magner, E., & Salis, A. (2018). Lipase Encapsulation onto ZIF-8: A Comparison between Biocatalysts Obtained at Low and High Zinc/2-Methylimidazole Molar Ratio in Aqueous Medium. Chemcatchem, 10(7), 1578-1585. doi:10.1002/cctc.201701984 [T1]
  85. Planchestainer, M., Roura Padrosa, D., Contente, M. L., & Paradisi, F. (2018). Genetically Fused T4L Acts as a Shield in Covalent Enzyme Immobilisation Enhancing the Rescued Activity. Catalysts, 8(1), 10. doi:10.3390/catal8010040 [P2]
  86. Planchestainer, M., Segaud, N., Shanmugam, M., McMaster, J., Paradisi, F., & Albrecht, M. (2018). Carbene in Cupredoxin Protein Scaffolds: Replacement of a Histidine Ligand in the Active Site Substantially Alters Copper Redox Properties. Angewandte Chemie-International Edition, 57(33), 10677-10682. doi:10.1002/anie.201807168 [P2]
  87. Potter, C. B., Davis, M. T., Albadarin, A. B., & Walker, G. M. (2018). Investigation of the Dependence of the Flory-Huggins Interaction Parameter on Temperature and Composition in a Drug-Polymer System. Molecular Pharmaceutics, 15(11), 5327-5335. doi:10.1021/acs.molpharmaceut.8b00797[P8][P9] [T8]
  88. Ramisetty, K. A., & Rasmuson, A. C. (2018). Controlling the Product Crystal Size Distribution by Strategic Application of Ultrasonication. Crystal Growth & Design, 18(3), 1697-1709. doi:10.1021/acs.cgd.7b01619 [LT2]
  89. Reen, F. J., Gutierrez-Barranquero, J. A., Parages, M. L., & O’Gara, F. (2018). Coumarin: a novel player in microbial quorum sensing and biofilm formation inhibition. Applied Microbiology and Biotechnology, 102(5), 2063-2073. doi:10.1007/s00253-018-8787-x [P1][P2]
  90. Reen, F. J., McGlacken, G. P., & O’Gara, F. (2018). The expanding horizon of alkyl quinolone signalling and communication in polycellular interactomes. Fems Microbiology Letters, 365(9), 10. doi:10.1093/femsle/fny076 [T3]
  91. Rokade, B. V., & Guiry, P. J. (2018). Axially Chiral P,N-Ligands: Some Recent Twists and Turns. Acs Catalysis, 8(1), 624-643. doi:10.1021/acscatal.7b03759 [P1]
  92. Serrano, D. R., Walsh, D., O’Connell, P., Mugheirbi, N. A., Worku, Z. A., Bolas-Fernandez, F., Healy, A. M. (2018). Optimising the in vitro and in vivo performance of oral cocrystal formulations via spray coating. European Journal of Pharmaceutics and Biopharmaceutics, 124, 13-27. doi:10.1016/j.ejpb.2017.11.015[P8][P9]
  93. Shaikh, R., Singh, R., Walker, G. M., & Croker, D. M. (2018). Pharmaceutical Cocrystal Drug Products: An Outlook on Product Development. Trends in Pharmacological Sciences, 39(12), 1033-1048. doi:10.1016/j.tips.2018.10.006 [P5]
  94. Shanahan, R. M., Hickey, A., Reen, F. J., O’Gara, F., & McGlacken, G. P. (2018). Synthesis of Benzofuroquinolines via Phosphine-Free Direct Arylation of 4-Phenoxyquinolines in Air. European Journal of Organic Chemistry(44), 6140-6149. doi:10.1002/ejoc.201800923 [T3]
  95. Sheehan, M., Ramasse, Q. M., Geaney, H., & Ryan, K. M. (2018). Linear heterostructured Ni2Si/Si nanowires with abrupt interfaces synthesised in solution. Nanoscale, 10(40), 19182-19187. doi:10.1039/c8nr05388j [LT2]
  96. Shiely, A. E., Clarke, L. A., Flynn, C. J., Buckley, A. M., Ford, A., Lawrence, S. E., & Maguire, A. R. (2018). Substrate and Catalyst Effects in the Enantioselective Copper-Catalysed C-H Insertion Reactions of alpha-Diazo-beta-oxo Sulfones. European Journal of Organic Chemistry(19), 2277-2289. doi:10.1002/ejoc.201800077 [P1][P2][P3]
  97. Shirazian, S., Darwish, S., Kuhs, M., Croker, D. M., & Walker, G. M. (2018). Regime-separated approach for population balance modelling of continuous wet granulation of pharmaceutical formulations. Powder Technology, 325, 420-428. doi:10.1016/j.powtec.2017.11.047 [P8][P9]
  98. Shirazian, S., Zeglinski, J., Darwish, S., Kuhs, M., Albadarin, A. B., Croker, D. M., & Walker, G. M. (2018). Continuous twin screw wet granulation: The combined effect of process parameters on residence time, particle size, and granule morphology. Journal of Drug Delivery Science and Technology, 48, 319-327. doi:10.1016/j.jddst.2018.09.016 [P8][P9]
  99. Simon, M., Donnellan, P., Glennon, B., & Jones, R. C. (2018). Resolution via Diastereomeric Salt Crystallization of Ibuprofen Lysine: Ternary Phase Diagram Studies. Chemical Engineering & Technology, 41(5), 921-927. doi:10.1002/ceat.201700427[P5]
  100. Sladek, S., Kearney, C., Crean, D., Brama, P. A. J., Tajber, L., Fawcett, K., Brayden, D. J. (2018). Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation. Drug Delivery and Translational Research, 8(5), 1421-1435. doi:10.1007/s13346-018-0557-x [P6][P8][P9]
  101. Souness, A., Zamboni, F., Walker, G. M., & Collins, M. N. (2018). Influence of scaffold design on 3D printed cell constructs. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 106(2), 533-545. doi:10.1002/jbm.b.33863 [P3]
  102. Steendam, R. R. E., Keshavarz, L., Blijlevens, M. A. R., de Souza, B., Croker, D. M., & Frawley, P. J. (2018). Effects of Scale-Up on the Mechanism and Kinetics of Crystal Nucleation. Crystal Growth & Design, 18(9), 5547-5555. doi:10.1021/acs.cgd.8b00857 [P7]
  103. Stokes, K., Fynn, G., Geaney, H., Bree, G., & Ryan, K. M. (2018). Axial Si-Ge Heterostructure Nanowires as Lithium-Ion Battery Anodes. Nano Letters, 18(9), 5569-5575. doi:10.1021/acs.nanolett.8b01988 [LT2]
  104. Suzuki, E. Y., Amaro, M. I., de Almeida, G. S., Cabral, L. M., Healy, A. M., & de Sousa, V. P. (2018). Development of a new formulation of roflumilast for pulmonary drug delivery to treat inflammatory lung conditions. International Journal of Pharmaceutics, 550(1-2), 89-99. doi:10.1016/j.ijpharm.2018.08.035[P8]
  105. Svard, M., Devi, K. R., Khamar, D., Mealey, D., Cheuk, D., Zeglinski, J., & Rasmuson, A. C. (2018). Solute clustering in undersaturated solutions systematic dependence on time, temperature and concentration. Physical Chemistry Chemical Physics, 20(22), 15550-15559. doi:10.1039/c8cp01509k [P4][P5][P7][
  106. Svard, M., Krishna, G. R., & Rasmuson, A. C. (2018). Synthesis, crystallisation and thermodynamics of two polymorphs of a new derivative of meglumine: 1-(2,2,3-trimethyl-1,3-oxazolidin-5-yl)-butane-1,2,3,4-tetrol. Crystengcomm, 20(1), 88-95. doi:10.1039/c7ce01135k [P4]
  107. Svärd, M., Devi, K.R., Khamar, D0, Mealey, D., Cheuk, D., Zeglinski, J.,& Rasmuson, Å.C..(2018) Nanoclustering in Isopropanol Solutions of Fenoxycarb. Phys.Chem.Chem.Phys, 20, 15550-15559. doi: 10.1039/c8cp01509k.[P5]
  108. Tan, S., Caparros-Martin, J. A., Matthews, V. B., Koch, H., O’Gara, F., Croft, K. D., & Ward, N. C. (2018). Isoquercetin and inulin synergistically modulate the gut microbiome to prevent development of the metabolic syndrome in mice fed a high fat diet. Scientific Reports, 8, 13. doi:10.1038/s41598-018-28521-8 [P2]
  109. Tyrrell, R., De Souza, B., & Frawley, P. J. (2018). Particle Breakage: Limiting Conditions for Crystal-Crystallizer Collisions. Crystal Growth & Design, 18(2), 617-622. doi:10.1021/acs.cgd.7b00125 [P7]
  110. Tyrrell, R., & Frawley, P. (2018). Single crystal fragmentation: Visualizing breakage model performance for pharmaceutical processes. Wear, 414, 275-288. doi:10.1016/j.wear.2018.08.024 [P7]
  111. Van den Akker, H. E. A. (2018). Lattice Boltzmann simulations for multi-scale chemical engineering. Current Opinion in Chemical Engineering, 21, 67-75. doi:10.1016/j.coche.2018.03.003 [MOMEnTUM]
  112. Verma, V., Bannigan, P., Lusi, M., Crowley, C. M., Hudson, S., Hodnett, B. K., & Davern, P. (2018). The heterogeneous crystallization of a novel solvate of clozapine base in the presence of excipients. Crystengcomm, 20(31), 4370-4382. doi:10.1039/c8ce00663f [P6]
  113. Verma, V., & Hodnett, B. K. (2018). A basis for the kinetic selection of polymorphs during solution crystallization of organic compounds. Crystengcomm, 20(37), 5551-5561. doi:10.1039/c8ce00843d [P6]
  114. Verma, V., Peddapatla, R. V. G., Crowley, C. M., Crean, A. M., Davern, P., Hudson, S., & Hodnett, B. K. (2018). Experimental Study on the Influence of Excipients on the Heterogeneous Crystallization and Dissolution Properties of an Active Pharmaceutical Ingredient. Crystal Growth & Design, 18(1), 338-350. doi:10.1021/acs.cgd.7b01336 [P6][T7]
  115. Verma, V., Zeglinski, J., Hudson, S., Davern, P., & Hodnett, B. K. (2018). Dependence of Heterogeneous Nucleation on Hydrogen Bonding Lifetime and Complementarity. Crystal Growth & Design, 18(11), 7158-7172. doi:10.1021/acs.cgd.8b01302 [P6]
  116. Walsh, D., Serrano, D. R., Worku, Z. A., Madi, A. M., O’Connell, P., Twamley, B., & Healy, A. M. (2018). Engineering of pharmaceutical cocrystals in an excipient matrix: Spray drying versus hot melt extrusion. International Journal of Pharmaceutics, 551(1-2), 241-256. doi:10.1016/j.ijpharm.2018.09.029 [P8]
  117. Walsh, D., Serrano, D. R., Worku, Z. A., Norris, B. A., & Healy, A. M. (2018). Production of cocrystals in an excipient matrix by spray drying. International Journal of Pharmaceutics, 536(1), 467-477. doi:10.1016/j.ijpharm.2017.12.020 [P8][P9]
  118. Wang, J., Radics, G., Whelehan, M., O’Driscoll, A., Healy, A. M., Gilmer, J. F., & Ledwidge, M. (2017). Novel Iron-Whey Protein Microspheres Protect Gut Epithelial Cells from Iron-Related Oxidative Stress and Damage and Improve Iron Absorption in Fasting Adults. Acta Haematologica, 138(4), 223-232. doi:10.1159/000480632 [T4]
  119. Wang, J. J., Liu, X., Milcovich, G., Chen, T. Y., Durack, E., Mallen, S., . . . Hudson, S. P. (2018). Co-reductive fabrication of carbon nanodots with high quantum yield for bioimaging of bacteria. Beilstein Journal of Nanotechnology, 9, 137-145. doi:10.3762/bjnano.9.16 [P4][P6]
  120. Xiao, X. X., & Magner, E. (2018). A quasi-solid-state and self-powered biosupercapacitor based on flexible nanoporous gold electrodes. Chemical Communications, 54(46), 5823-5826. doi:10.1039/c8cc02555j [T1]
  121. Xiao, X. X., Siepenkoetter, T., Conghaile, P. O., Leech, D., & Magner, E. (2018). Nanoporous Gold-Based Biofuel Cells on Contact Lenses. Acs Applied Materials & Interfaces, 10(8), 7107-7116. doi:10.1021/acsami.7b18708[T1]
  122. Yousuf, M., & Frawley, P. J. (2018). Experimental Evaluation of Fluid Shear Stress Impact on Secondary Nucleation in a Solution Crystallization of Paracetamol. Crystal Growth & Design, 18(11), 6843-6852. doi:10.1021/acs.cgd.8b01074[P7]
  123. Zarski, P., & Ryder, A. G. (2018). Super Stable Fluorescein Isothiocyanate Isomer I Monolayer for Total Internal Reflection Fluorescence Microscopy. Langmuir, 34(37), 10913-10923. doi:10.1021/acs.langmuir.8b02509 [T5]
  124. Zeglinski, J., Kuhs, M., Khamar, D., Hegarty, A. C., Devi, R. K., & Rasmuson, A. C. (2018). Crystal Nucleation of Tolbutamide in Solution: Relationship to Solvent, Solute Conformation, and Solution Structure. Chemistry-a European Journal, 24(19), 4916-4926. doi:10.1002/chem.201705954 [P5]

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