Publications - 2017

SSPC, the Science Foundation Ireland (SFI) Research Centre for Pharmaceuticals

  1. Acevedo, D., Kamaraju, V. K., Glennon, B., & Nagy, Z. K. (2017). Modeling and Characterization of an in Situ Wet Mill Operation. Organic Process Research & Development, 21(7), 1069-1079. doi:10.1021/acs.oprd.7b00192
  2. Ahuja, D., Bannigan, P., & Rasmuson, A. C. (2017). Study of three solvates of sulfamethazine. Crystengcomm, 19(43), 6481-6488. doi:10.1039/c7ce01610g
  3. Albadarin, A. B., Collins, M. N., Naushad, M., Shirazian, S., Walker, G., & Mangwandi, C. (2017). Activated lignin-chitosan extruded blends for efficient adsorption of methylene blue. Chemical Engineering Journal, 307, 264-272. doi:10.1016/j.cej.2016.08.089
  4. Albadarin, A. B., Lewis, T. D., & Walker, G. M. (2017). Granulated polyhalite fertilizer caking propensity. Powder Technology, 308, 193-199. doi:10.1016/j.powtec.2016.12.004
  5. Aljohani, M., Pallipurath, A. R., McArdle, P., & Erxleben, A. (2017). A Comprehensive Cocrystal Screening Study of Chlorothiazide. Crystal Growth & Design, 17(10), 5223-5232. doi:10.1021/acs.cgd.7b00745
  6. Asghar, M. A., Ahmed, A., Zahir, E., Iqbal, J., & Walker, G. (2017). Incidence of aflatoxins contamination in dry fruits and edible nuts collected from Pakistan. Food Control, 78, 169-175. doi:10.1016/j.foodcont.2017.02.058
  7. Balzarini, J., Menni, M., Das, K., van Berckelaer, L., Ford, A., Maguire, N. M., . . . Maguire, A. R. (2017). Guanine alpha-carboxy nucleoside phosphonate (G-alpha-CNP) shows a different inhibitory kinetic profile against the DNA polymerases of human immunodeficiency virus (HIV) and herpes viruses. Biochemical Pharmacology, 136, 51-61. doi:10.1016/j.bcp.2017.04.001
  8. Bannigan, P., Durack, E., Madden, C., Lusi, M., & Hudson, S. P. (2017). Role of Biorelevant Dissolution Media in the Selection of Optimal Salt Forms of Oral Drugs: Maximizing the Gastrointestinal Solubility and in Vitro Activity of the Antimicrobial Molecule, Clofazimine. Acs Omega, 2(12), 8969-8981. doi:10.1021/acsomega.7b01454
  9. Blackshields, C. A., & Crean, A. M. (2018). Continuous powder feeding for pharmaceutical solid dosage form manufacture: a short review. Pharmaceutical Development and Technology, 23(6), 554-560. doi:10.1080/10837450.2017.1339197
  10. Buckley, K., & Ryder, A. G. (2017). Applications of Raman Spectroscopy in Biopharmaceutical Manufacturing: A Short Review. Applied Spectroscopy, 71(6), 1085-1116. doi:10.1177/0003702817703270
  11. Bueno, R. A., Crowley, C. M., Hodnett, B. K., Hudson, S., & Davern, P. (2017). Influence of Process Parameters on the Heterogeneous Nucleation of Active Pharmaceutical Ingredients onto Excipients. Organic Process Research & Development, 21(4), 559-570. doi:10.1021/acs.oprd.6b00425
  12. Buzid, A., Reen, F. J., Langsi, V. K., Muimhneachain, E. O., O’Gara, F., McGlacken, G. P., . . . Glennon, J. D. (2017). Direct and Rapid Electrochemical Detection of Pseudomonas aeruginosa Quorum Signaling Molecules in Bacterial Cultures and Cystic Fibrosis Sputum Samples through Cationic Surfactant-Assisted Membrane Disruption. Chemelectrochem, 4(3), 533-541. doi:10.1002/celc.201600590
  13. Cassidy, J., Bruen, L., Rosini, E., Molla, G., Pollegioni, L., & Paradisi, F. (2017). Engineering substrate promiscuity in halophilic alcohol dehydrogenase (HvADH2) by in silico design. Plos One, 12(11). doi:10.1371/journal.pone.0187482
  14. Clarke, S. L., & McGlacken, G. P. (2017). Methyl fluorosulfonyldifluoroacetate (MFSDA): An Underutilised Reagent for Trifluoromethylation. Chemistry-a European Journal, 23(6), 1219-1230. doi:10.1002/chem.201602511
  15. Castro-Dominguez, B., Moroney, K., Schaller, B., O’Connor, S., Cloonan, A., Vo, T. T. N., . . . O’Reilly, E. J. (2017). Electrospun API-loaded mixed matrix membranes for controlled release. Rsc Advances, 7(68), 43300-43309. doi:10.1039/c7ra08600h
  16. Contente, M. L., Dall’Oglio, F., Tamborini, L., Molinari, F., & Paradisi, F. (2017). Highly Efficient Oxidation of Amines to Aldehydes with Flow-based Biocatalysis. Chemcatchem, 9(20), 3843-3848. doi:10.1002/cctc.201701147
  17. Crawford, D. E., Miskimmin, C. K. G., Albadarin, A. B., Walker, G., & James, S. L. (2017). Organic synthesis by Twin Screw Extrusion (TSE): continuous, scalable and solvent-free. Green Chemistry, 19(6), 1507-1518. doi:10.1039/c6gc03413f
  18. Crowley, M. E., Hegarty, A., McAuliffe, M. A. P., O’Mahony, G. E., Kiernan, L., Hayes, K., & Crean, A. M. (2017). Near-infrared monitoring of roller compacted ribbon density: Investigating sources of variation contributing to noisy spectral data. European Journal of Pharmaceutical Sciences, 102, 103-114. doi:10.1016/j.ejps.2017.02.024
  19. Davis, M. T., Potter, C. B., Mohammadpour, M., Albadarin, A. B., & Walker, G. M. (2017). Design of spray dried ternary solid dispersions comprising itraconazole, soluplus and HPMCP: Effect of constituent compositions. International Journal of Pharmaceutics, 519(1-2), 365-372. doi:10.1016/j.ijpharm.2017.01.043
  20. de Souza, B., Keshavarz, L., Cogoni, G., & Frawley, P. J. (2017). Pressurized-Synthetic Methodology for Solubility Determination at Elevated Temperatures with Application to Paracetamol in Pure Solvents. Journal of Chemical and Engineering Data, 62(5), 1689-1700. doi:10.1021/acs.jced.7b00118
  21. Despotopoulou, C., McKeon, S. C., Connon, R., Coeffard, V., Muller-Bunz, H., & Guiry, P. J. (2017). Application of a One-Pot Friedel-Crafts Alkylation/Michael Addition Methodology to the Asymmetric Synthesis of Ergoline Derivatives. European Journal of Organic Chemistry(45), 6734-6738. doi:10.1002/ejoc.201701480
  22. Dul, M., Paluch, K. J., Healy, A. M., Sasse, A., & Tajber, L. (2017). Optimisation of the self-assembly process: production of stable, alginate-based polyelectrolyte nanocomplexes with protamine. Journal of Nanoparticle Research, 19(6). doi:10.1007/s11051-017-3901-z
  23. Foley, A. M., Gavin, D. P., Joniec, I., & Maguire, A. R. (2017). Impact of variation of the acyl group on the efficiency and selectivity of the lipase-mediated resolution of 2-phenylalkanols. Tetrahedron-Asymmetry, 28(9), 1144-1153. doi:10.1016/j.tetasy.2017.08.002
  24. Gavin, D. P., Foley, A., Moody, T. S., Khandavilli, U. B. R., Lawrence, S. E., O’Neill, P., & Maguire, A. R. (2017). Hydrolase-mediated resolution of the hemiacetal in 2-chromanols: The impact of remote substitution. Tetrahedron-Asymmetry, 28(4), 577-585. doi:10.1016/j.tetasy.2017.04.001
  25. Gniado, K., MacFhionnghaile, P., McArdle, P., & Erxleben, A. (2018). The natural bile acid surfactant sodium taurocholate (NaTC) as a coformer in coamorphous systems: Enhanced physical stability and dissolution behavior of coamorphous drug-NaTc systems. International Journal of Pharmaceutics, 535(1-2), 132-139. doi:10.1016/j.ijpharm.2017.10.049
  26. Healy, A. M., Worku, Z. A., Kumar, D., & Madi, A. M. (2017). Pharmaceutical solvates, hydrates and amorphous forms: A special emphasis on cocrystals. Advanced Drug Delivery Reviews, 117, 25-46. doi:10.1016/j.addr.2017.03.002
  27. Heffernan, C., Ukrainczyk, M., Gamidi, R. K., Hodnett, B. K., & Rasmuson, A. C. (2017). Extraction and Purification of Curcuminoids from Crude Curcumin by a Combination of Crystallization and Chromatography. Organic Process Research & Development, 21(6), 821-826. doi:10.1021/acs.oprd.6b00347
  28. Jia, L. J., Svard, M., & Rasmuson, A. C. (2017). Crystal Growth of Salicylic Acid in Organic Solvents. Crystal Growth & Design, 17(6), 2964-2974. doi:10.1021/acs.cgd.6b01415
  29. Kelly, P. S., Clarke, C., Costello, A., Monger, C., Meiller, J., Dhiman, H., . . . Barron, N. (2017). Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells. Metabolic Engineering, 41, 11-22. doi:10.1016/j.ymben.2017.02.001
  30. Khandavilli, U. B. R., Bhogala, B. R., Maguire, A. R., & Lawrence, S. E. (2017). Symmetry assisted tuning of bending and brittle multi-component forms of probenecid. Chemical Communications, 53(23), 3381-3384. doi:10.1039/c7cc01091e
  31. Kingston, C., & Guiry, P. J. (2017). Enantiodivergent Synthesis of Tertiary alpha-Aryl 1-Indanones: Evidence Toward Disparate Mechanisms in the Palladium-Catalyzed Decarboxylative Asymmetric Protonation. Journal of Organic Chemistry, 82(7), 3806-3819. doi:10.1021/acs.joc.7b00303
  32. Kuhs, M., Moore, J., Kollamaram, G., Walker, G., & Croker, D. (2017). Predicting optimal wet granulation parameters for extrusion-spheronisation of pharmaceutical pellets using a mixer torque rheometer. International Journal of Pharmaceutics, 517(1-2), 19-24. doi:10.1016/j.ijpharm.2016.11.057
  33. Kumar, V., & Connon, S. J. (2017). Direct, efficient NHC-catalysed aldehyde oxidative amidation: in situ formed benzils as unconventional acylating agents. Chemical Communications, 53(73), 10212-10215. doi:10.1039/c7cc05561g
  34. Lamy, B., Tewes, F., Serrano, D. R., Lamarche, I., Gobin, P., Couet, W., . . . Marchand, S. (2018). New aerosol formulation to control ciprofloxacin pulmonary concentration. Journal of Controlled Release, 271, 118-126. doi:10.1016/j.jconrel.2017.12.021
  35. Li, B. Y., Casamayou-Boucau, Y., Calvet, A., & Ryder, A. G. (2017). Chemometric approaches to low-content quantification (LCQ) in solid-state mixtures using Raman mapping spectroscopy. Analytical Methods, 9(44), 6293-6301. doi:10.1039/c7ay01778b
  36. Lin, Y. Y., Kurniawan, T. A., Albadarin, A. B., & Walker, G. (2018). Enhanced removal of acetaminophen from synthetic wastewater using multi-walled carbon nanotubes (MWCNTs) chemically modified with NaOH, HNO3/H2SO4, ozone, and/or chitosan. Journal of Molecular Liquids, 251, 369-377. doi:10.1016/j.molliq.2017.12.051
  37. Mc Gillicuddy, A., Kelly, M., Crean, A. M., & Sahm, L. J. (2017). The knowledge, attitudes and beliefs of patients and their healthcare professionals around oral dosage form modification: A systematic review of the qualitative literature. Research in Social & Administrative Pharmacy, 13(4), 717-726. doi:10.1016/j.sapharm.2016.09.004
  38. McCarthy, C. A., Faisal, W., O’Shea, J. P., Murphy, C., Ahern, R. J., Ryan, K. B., . . . Crean, A. M. (2017). In vitro dissolutionmodels for the prediction of in vivo performance of an oral mesoporous silica formulation. Journal of Controlled Release, 250, 86-95. doi:10.1016/j.jconrel.2016.12.043
  39. McCaw, P. G., Buckley, N. M., Eccles, K. S., Lawrence, S. E., Maguire, A. R., & Callins, S. G. (2017). Synthesis of Cyclic alpha-Diazo-beta-keto Sulfoxides in Batch and Continuous Flow. Journal of Organic Chemistry, 82(7), 3666-3679. doi:10.1021/acs.joc.7b00172
  40. Mc Gillicuddy, A., Crean, A. M., Kelly, M., & Sahm, L. (2017). Oral medicine modification for older adults: a qualitative study of nurses. Bmj Open, 7(12). doi:10.1136/bmjopen-2017-018151
  41. Mesallati, H., Conroy, D., Hudson, S., & Tajber, L. (2017). Preparation and characterization of amorphous ciprofloxacin-amino acid salts. European Journal of Pharmaceutics and Biopharmaceutics, 121, 73-89. doi:10.1016/j.ejpb.2017.09.009
  42. Mesallati, H., & Tajber, L. (2017). Polymer/Amorphous Salt Solid Dispersions of Ciprofloxacin. Pharmaceutical Research, 34(11), 2425-2439. doi:10.1007/s11095-017-2250-z
  43. Mesallati, H., Umerska, A., Paluch, K. J., & Tajber, L. (2017). Amorphous Polymeric Drug Salts as Ionic Solid Dispersion Forms of Ciprofloxacin. Molecular Pharmaceutics, 14(7), 2209-2223. doi:10.1021/acs.molpharmaceut.7b00039
  44. Moynihan, H. K., & Horgan, D. E. (2017). Impurity Occurrence and Removal in Crystalline Products from Process Reactions. Organic Process Research & Development, 21(5), 689-704. doi:10.1021/acs.oprd.6b00403
  45. Mugheirbi, N. A., O’Connell, P., Serrano, D. R., Healy, A. M., Taylor, L. S., & Tajber, L. (2017). A Comparative Study on the Performance of Inert and Functionalized Spheres Coated with Solid Dispersions Made of Two Structurally Related Antifungal Drugs. Molecular Pharmaceutics, 14(11), 3718-3728. doi:10.1021/acs.molpharmaceut.7b00482
  46. Muimhneachain, E. O., Pardo, L. M., Bateman, L. M., Khandavilli, U. B. R., Lawrence, S. E., & McGlacken, G. P. (2017). Intramolecular Direct Arylation of 1,3-Diketone-Derived Enol Ethers in a Synthesis of Tricyclic Oxoisochromene Derivatives. Advanced Synthesis & Catalysis, 359(9), 1529-1534. doi:10.1002/adsc.201700062
  47. Muimhneachain, E. O., Reen, F. J., O’Gara, F., & McGlacken, G. P. (2018). Analogues of Pseudomonas aeruginosa signalling molecules to tackle infections. Organic & Biomolecular Chemistry, 16(2), 169-179. doi:10.1039/c7ob02395b
  48. Nikitin, K., Jennings, E. V., Al Sulaimi, S., Ortin, Y., & Gilheany, D. G. (2018). Dynamic Cross‐Exchange in Halophosphonium Species: Direct Observation of Stereochemical Inversion in the Course of an SN2 Process. Angewandte Chemie International Edition, 57(6), 1480-1484.
  49. Nottingham, C., Muller-Bunz, H., McGlinchey, M. J., & Guiry, P. J. (2017). Controlling the Reactivity of Ferrocenyl Carbocations: Routes to Enantiomerically Pure Chlorophosphites and Solid-State Characterization of a Benzopentalene Dimer. European Journal of Organic Chemistry(19), 2848-2854. doi:10.1002/ejoc.201700430
  50. O’Mahony, R. M., Lynch, D., Hayes, H. L. D., Ni Thuama, E., Donnellan, P., Jones, R. C., . . . Maguire, A. R. (2017). Exploiting the Continuous in situ Generation of Mesyl Azide for Use in a Telescoped Process. European Journal of Organic Chemistry(44), 6533-6539. doi:10.1002/ejoc.201700871
  51. Padrela, L., Zeglinski, J., & Ryan, K. M. (2017). Insight into the Role of Additives in Controlling Polymorphic Outcome: A CO2-Antisolvent Crystallization Process of Carbamazepine. Crystal Growth & Design, 17(9), 4544-4553. doi:10.1021/acs.cgd.7b00163
  52. Pallipurath, A. R., Civati, F., Sibik, J., Crowley, C., Zeitler, J. A., McArdle, P., & Erxleben, A. (2017). A comprehensive spectroscopic study of the polymorphs of diflunisal and their phase transformations. International Journal of Pharmaceutics, 528(1-2), 312-321. doi:10.1016/j.ijpharm.2017.06.020
  53. Peddapatla, R. V. G., Ahmed, M. R., Blackshields, C. A., Sousa-Gallagher, M. J., McSweeney, S., Kruse, J., . . . Fitzpatrick, D. (2018). Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): A Novel Approach To Investigate the Wettability of Pharmaceutical Powder Blends. Molecular Pharmaceutics, 15(1), 31-39. doi:10.1021/acs.molpharmaceut.7b00658
  54. Planchestainer, M., Contente, M. L., Cassidy, J., Molinari, F., Tamborini, L., & Paradisi, F. (2017). Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata. Green Chemistry, 19(2), 372-375. doi:10.1039/c6gc01780k
  55. Potter, C. B., Kollamaram, G., Zeglinski, J., Whitaker, D. A., Croker, D. M., & Walker, G. M. (2017). Investigation of polymorphic transitions of piracetam induced during wet granulation. European Journal of Pharmaceutics and Biopharmaceutics, 119, 36-46. doi:10.1016/j.ejpb.2017.05.012
  56. Prendergast, A. M., & McGlacken, G. P. (2017). Regioselective Chlorination and Suzuki-Miyaura Cross-Coupling of 4-Alkoxycoumarins, 4-Alkoxy-2-pyrones, and Related Heterocycles. European Journal of Organic Chemistry(32), 4827-4835. doi:10.1002/ejoc.201700837
  57. Prendergast, A. M., Pardo, L. M., Fairlamb, I. J. S., & McGlacken, G. P. (2017). Access to Some C5-Cyclised 2-Pyrones and 2-Pyridones via Direct Arylation; Retention of Chloride as a Synthetic Handle. European Journal of Organic Chemistry(34), 5119-5124. doi:10.1002/ejoc.201700980
  58. Rokade, B. V., & Guiry, P. J. (2017). Diastereofacial pi-Stacking as an Approach To Access an Axially Chiral P,N-Ligand for Asymmetric Catalysis. Acs Catalysis, 7(4), 2334-2338. doi:10.1021/acscatal.6b03427
  59. Rolon, M., Serrano, D. R., Lalatsa, A., de Pablo, E., Torrado, J. J., Ballesteros, M. P., . . . Dea-Ayuela, M. A. (2017). Engineering Oral and Parenteral Amorphous Amphotericin B Formulations against Experimental Trypanosoma cruzi Infections. Molecular Pharmaceutics, 14(4), 1095-1106. doi:10.1021/acs.molpharmaceut.6b01034
  60. Romeih, E., & Walker, G. (2017). Recent advances on microbial transglutaminase and dairy application. Trends in Food Science & Technology, 62, 133-140. doi:10.1016/j.tifs.2017.02.015
  61. Sajjia, M., Shirazian, S., Egan, D., Iqbal, J., Albadarin, A. B., Southern, M., & Walker, G. (2017). Mechanistic modelling of industrial-scale roller compactor ‘Freund TF-MINI model’. Computers & Chemical Engineering, 104, 141-150. doi:10.1016/j.compchemeng.2017.04.018
  62. Sajjia, M., Shirazian, S., Kelly, C. B., Albadarin, A. B., & Walker, G. (2017). ANN Analysis of a Roller Compaction Process in the Pharmaceutical Industry. Chemical Engineering & Technology, 40(3), 487-492. doi:10.1002/ceat.201600229
  63. Serrano, D. R., Walsh, D., O’Connell, P., Mugheirbi, N. A., Worku, Z. A., Bolas-Fernandez, F., . . . Healy, A. M. (2018). Optimising the in vitro and in vivo performance of oral cocrystal formulations via spray coating. European Journal of Pharmaceutics and Biopharmaceutics, 124, 13-27. doi:10.1016/j.ejpb.2017.11.015
  64. Shiely, A. E., Slattery, C. N., Ford, A., Eccles, K. S., Lawrence, S. E., & Maguire, A. R. (2017). Enantioselective copper catalysed intramolecular C-H insertion reactions of alpha-diazo-beta-keto sulfones, alpha-diazo-beta-keto phosphine oxides and 2-diazo-1,3-diketones; the influence of the carbene substituent. Organic & Biomolecular Chemistry, 15(12), 2609-2628. doi:10.1039/c7ob00214a
  65. Shirazian, S., Darwish, S., Kuhs, M., Croker, D. M., & Walker, G. M. (2018). Regime-separated approach for population balance modelling of continuous wet granulation of pharmaceutical formulations. Powder Technology, 325, 420-428. doi:10.1016/j.powtec.2017.11.047
  66. Shirazian, S., Kuhs, M., Darwish, S., Croker, D., & Walker, G. M. (2017). Artificial neural network modelling of continuous wet granulation using a twin-screw extruder. International Journal of Pharmaceutics, 521(1-2), 102-109. doi:10.1016/j.ijpharm.2017.02.009
  67. Simon, A., Amaro, M. I., Healy, A. M., Cabral, L. M., & de Sousa, V. P. (2017). Development of a Discriminative In Vitro Release Test for Rivastigmine Transdermal Patches Using Pharmacopeial Apparatuses: USP 5 and USP 6. Aaps Pharmscitech, 18(7), 2561-2569. doi:10.1208/s12249-017-0738-9
  68. Souness, A., Zamboni, F., Walker, G. M., & Collins, M. N. (2018). Influence of scaffold design on 3D printed cell constructs. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 106(2), 533-545. doi:10.1002/jbm.b.33863
  69. Svard, M., Krishna, G. R., & Rasmuson, A. C. (2018). Synthesis, crystallisation and thermodynamics of two polymorphs of a new derivative of meglumine: 1-(2,2,3-trimethyl-1,3-oxazolidin-5-yl)-butane-1,2,3,4-tetrol. Crystengcomm, 20(1), 88-95. doi:10.1039/c7ce01135k
  70. Tierney, T. B., Rasmuson, A. C., & Hudson, S. P. (2017). Size and Shape Control of Micron-Sized Salicylic Acid Crystals during Antisolvent Crystallization. Organic Process Research & Development, 21(11), 1732-1740. doi:10.1021/acs.oprd.7b00181
  71. Todaro, V., Persoons, T., Grove, G., Healy, A. M., & D’Arcy, D. M. (2017). Characterization and Simulation of Hydrodynamics in the Paddle, Basket and Flow-Through Dissolution Testing Apparatuses – A Review. Dissolution Technologies, 24(3), 24-36. doi:10.14227/dt240317p24
  72. Tully, G., Hou, G. Y., & Glennon, B. (2016). Solubility of Benzoic Acid and Aspirin in Pure Solvents Using Focused Beam Reflective Measurement. Journal of Chemical and Engineering Data, 61(1), 594-601. doi:10.1021/acs.jced.5b00746
  73. Umerska, A., Corrigan, O. I., & Tajber, L. (2017). Design of chondroitin sulfate-based polyelectrolyte nanoplexes: Formation of nanocarriers with chitosan and a case study of salmon calcitonin. Carbohydrate Polymers, 156, 276-284. doi:10.1016/j.carbpol.2016.09.035
  74. Verma, V., Peddapatla, R. V. G., Crowley, C. M., Crean, A. M., Davern, P., Hudson, S., & Hodnett, B. K. (2018). Experimental Study on the Influence of Excipients on the Heterogeneous Crystallization and Dissolution Properties of an Active Pharmaceutical Ingredient. Crystal Growth & Design, 18(1), 338-350. doi:10.1021/acs.cgd.7b01336
  75. Walsh, D., Serrano, D. R., Worku, Z. A., Norris, B. A., & Healy, A. M. (2018). Production of cocrystals in an excipient matrix by spray drying. International Journal of Pharmaceutics, 536(1), 467-477. doi:10.1016/j.ijpharm.2017.12.020
  76. Worku, Z. A., Kumar, D., Gomes, J. V., He, Y. L., Glennon, B., Ramisetty, K. A., . . . Healy, A. M. (2017). Modelling and understanding powder flow properties and compactability of selected active pharmaceutical ingredients, excipients and physical mixtures from critical material properties. International Journal of Pharmaceutics, 531(1), 191-204. doi:10.1016/j.ijpharm.2017.08.063

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