Publications

Publications - 2013

SSPC increased it's reputation globally through a large number of peer reviewed high impact publications done by a diverse range of academic expertise

  1. Ahern, R. J., Hanrahan, J. P., Tobin, J. M., Ryan, K. B., & Crean, A. M. (2013). Comparison of fenofibrate-mesoporous silica drug-loading processes for enhanced drug delivery. European Journal of Pharmaceutical Sciences, 50(3-4), 400-409. doi:10.1016/j.ejps.2013.08.026
  2. Bianco, S., Tewes, F., Tajber, L., Caron, V., Corrigan, O. I., & Healy, A. M. (2013). Bulk, surface properties and water uptake mechanisms of salt/acid amorphous composite systems. International Journal of Pharmaceutics, 456(1), 143-152. doi:10.1016/j.ijpharm.2013.07.076
  3. Caron, V., Hu, Y., Tajber, L., Erxleben, A., Corrigan, O. I., McArdle, P., & Healy, A. M. (2013). Amorphous Solid Dispersions of Sulfonamide/Soluplus (R) and Sulfonamide/PVP Prepared by Ball Milling. Aaps Pharmscitech, 14(1), 464-474. doi:10.1208/s12249-013-9931-7
  4. Croker, D. M., Davey, R. J., Rasmuson, A. C., & Seaton, C. C. (2013a). Nucleation in the p-Toluenesulfonamide/Triphenylphosphine Oxide Co-crystal System. Crystal Growth & Design, 13(8), 3754-3762. doi:10.1021/cg400780e
  5. Croker, D. M., Davey, R. J., Rasmuson, A. C., & Seaton, C. C. (2013b). Solution mediated phase transformations between co-crystals. Crystengcomm, 15(11), 2044-2047. doi:10.1039/c2ce26801a
  6. Curtin, V., Amharar, Y., Gallagher, K. H., Corcoran, S., Tajber, L., Corrigan, O. I., & Healy, A. M. (2013). Reducing mechanical activation-induced amorphisation of salbutamol sulphate by co-processing with selected carboxylic acids. International Journal of Pharmaceutics, 456(2), 508-516. doi:10.1016/j.ijpharm.2013.08.025
  7. Curtin, V., Amharar, Y., Hu, Y., Erxleben, A., McArdle, P., Caron, V., . . . Healy, A. M. (2013). Investigation of the Capacity of Low Glass Transition Temperature Excipients to Minimize Amorphization of Sulfadimidine on Comilling. Molecular Pharmaceutics, 10(1), 386-396. doi:10.1021/mp300529a
  8. Dai, L., Liu, Y. Q., Liu, J. Y., Wen, X. M., Xu, Z. S., Wang, Z., . . . Ye, T. (2013). A novel CyclinE/CyclinA-CDK Inhibitor targets p27(Kip1) degradation, cell cycle progression and cell survival: Implications in cancer therapy. Cancer Letters, 333(1), 103-112. doi:10.1016/j.canlet.2013.01.025
  9. Deasy, R. E., Moody, T. S., & Maguire, A. R. (2013). Influence of the position of the substituent on the efficiency of lipase-mediated resolutions of 3-aryl alkanoic acids. Tetrahedron-Asymmetry, 24(23), 1480-1487. doi:10.1016/j.tetasy.2013.09.019
  10. Duffy, D., Barrett, M., & Glennon, B. (2013). Novel, Calibration-Free Strategies for Supersaturation Control in Antisolvent Crystallization Processes. Crystal Growth & Design, 13(8), 3321-3332. doi:10.1021/cg301673g
  11. Eccles, K. S., Morrison, R. E., Daly, C. A., O’Mahony, G. E., Maguire, A. R., & Lawrence, S. E. (2013). Co-crystallisation through halogen bonding with racemic or enantiopure sulfinamides. Crystengcomm, 15(37), 7571-7575. doi:10.1039/c3ce40932e
  12. Ferguson, S., Morris, G., Hao, H. X., Barrett, M., & Glennon, B. (2013). Characterization of the anti-solvent batch, plug flow and MSMPR crystallization of benzoic acid. Chemical Engineering Science, 104, 44-54. doi:10.1016/j.ces.2013.09.006
  13. Glocheux, Y., Pasarin, M. M., Albadarin, A. B., Allen, S. J., & Walker, G. M. (2013). Removal of arsenic from groundwater by adsorption onto an acidified laterite by-product. Chemical Engineering Journal, 228, 565-574. doi:10.1016/j.cej.2013.05.043
  14. Godinho, B., Ogier, J. R., Darcy, R., Driscoll, C. M., & Cryan, J. F. (2013). Self-assembling Modified beta-Cyclodextrin Nanoparticles as Neuronal siRNA Delivery Vectors: Focus on Huntington’s Disease. Molecular Pharmaceutics, 10(2), 640-649. doi:10.1021/mp3003946
  15. Hayes, J. A., Eccles, K. S., Elcoate, C. J., Daly, C. A., Lawrence, S. E., & Moynihan, H. A. (2013). Crystal Polymorphism of Methyl 2,3,4-tri-O-acetyl-1-O-(trichloroacetimidoyl)-alpha-D-glucopyranouronate. Journal of Chemical Crystallography, 43(3), 138-143. doi:10.1007/s10870-013-0397-y
  16. Hennigan, M. C., & Ryder, A. G. (2013). Quantitative polymorph contaminant analysis in tablets using Raman and near infra-red spectroscopies. Journal of Pharmaceutical and Biomedical Analysis, 72, 163-171. doi:10.1016/j.jpba.2012.10.002
  17. Hu, Y., Erxleben, A., Hodnett, B. K., Li, B. Y., McArdle, P., Rasmuson, A. C., & Ryder, A. G. (2013). Solid-State Transformations of Sulfathiazole Polymorphs: The Effects of Milling and Humidity. Crystal Growth & Design, 13(8), 3404-3413. doi:10.1021/cg4002779
  18. Hu, Y., Macfhionnghaile, P., Caron, V., Tajber, L., Healy, A. M., Erxleben, A., & McArdle, P. (2013). Formation, physical stability, and quantification of process-induced disorder in cryomilled samples of a model polymorphic drug. Journal of Pharmaceutical Sciences, 102(1), 93-103. doi:10.1002/jps.23338
  19. Karpinska, J., Erxleben, A., & McArdle, P. (2013). Applications of Low Temperature Gradient Sublimation in Vacuo: Rapid Production of High Quality Crystals. The First Solvent-Free Crystals of Ethinyl Estradiol. Crystal Growth & Design, 13(3), 1122-1130. doi:10.1021/cg301479c
  20. Khraisheh, M., Kim, J., Campos, L., Al-Muhtaseb, A. H., Walker, G. M., & AlGhouti, M. (2013). Removal of Carbamazepine from Water by a Novel TiO2-Coconut Shell Powder/UV Process: Composite Preparation and Photocatalytic Activity. Environmental Engineering Science, 30(9), 515-526. doi:10.1089/ees.2012.0056
  21. Kuhs, M., Svard, M., & Rasmuson, A. C. (2013). Thermodynamics of fenoxycarb in solution. Journal of Chemical Thermodynamics, 66, 50-58. doi:10.1016/j.jct.2013.06.007
  22. Liu, H., Liu, Y. Q., Wang, Z., Xing, X. Y., Maguire, A. R., Luesch, H., . . . Ye, T. (2013). Total Synthesis and Biological Evaluation of Grassypeptolide A. Chemistry-a European Journal, 19(21), 6774-6784. doi:10.1002/chem.201203667
  23. MacFhionnghaile, P., Hu, Y., McArdle, P., & Erxleben, A. (2013). A comprehensive near infrared spectroscopic study of the limits of quantitative analysis of sulfathiazole polymorphism. Journal of near Infrared Spectroscopy, 21(1), 55-66. doi:10.1255/jnirs.1036
  24. Magee, T. R. A., McMinn, W. A. M., Farrell, G., Topley, L., Al-Degs, Y. S., Walker, G. M., & Khraisheh, M. (2013). Moisture and temperature dependence of the dielectric properties of pharmaceutical powders. Journal of Thermal Analysis and Calorimetry, 111(3), 2157-2164. doi:10.1007/s10973-012-2739-y
  25. Mangwandi, C., Albadarin, A. B., Al-Muhtaseb, A. H., Allen, S. J., & Walker, G. M. (2013). Optimisation of high shear granulation of multicomponent fertiliser using response surface methodology. Powder Technology, 238, 142-150. doi:10.1016/j.powtec.2012.03.047
  26. Mangwandi, C., Liu, J. T., Albadarin, A. B., Allen, S. J., & Walker, G. M. (2013). Alternative method for producing organic fertiliser from anaerobic digestion liquor and limestone powder: High Shear wet granulation. Powder Technology, 233, 245-254. doi:10.1016/j.powtec.2012.09.017
  27. McCarthy, J., O’Neill, M. J., Bourre, L., Walsh, D., Quinlan, A., Hurley, G., . . . O’Driscoll, C. M. (2013). Gene silencing of TNF-alpha in a murine model of acute colitis using a modified cyclodextrin delivery system. Journal of Controlled Release, 168(1), 28-34. doi:10.1016/j.jconrel.2013.03.004
  28. Moynihan, H. A., Hayes, J. A., Eccles, K. S., Coles, S. J., & Lawrence, S. E. (2013). Hydrogen bonding in crystal forms of primary amide functionalised glucose and cellobiose. Carbohydrate Research, 374, 29-39. doi:10.1016/j.carres.2013.03.024
  29. O’Mahony, A. M., Desgranges, S., Ogier, J., Quinlan, A., Devocelle, M., Darcy, R., . . . O’Driscoll, C. M. (2013). In Vitro Investigations of the Efficacy of Cyclodextrin-siRNA Complexes Modified with Lipid-PEG-Octaarginine: Towards a Formulation Strategy for Non-viral Neuronal siRNA Delivery. Pharmaceutical Research, 30(4), 1086-1098. doi:10.1007/s11095-012-0945-8
  30. O’Mahony, A. M., Godinho, B., Cryan, J. F., & O’Driscoll, C. M. (2013). Non-Viral Nanosystems for Gene and Small Interfering RNA Delivery to the Central Nervous System: Formulating the Solution. Journal of Pharmaceutical Sciences, 102(10), 3469-3484. doi:10.1002/jps.23672
  31. O’Mahony, A. M., Ogier, J., Darcy, R., Cryan, J. F., & O’Driscoll, C. M. (2013). Cationic and PEGylated Amphiphilic Cyclodextrins: Co-Formulation Opportunities for Neuronal Sirna Delivery. Plos One, 8(6), 9. doi:10.1371/journal.pone.0066413
  32. O’Mahony, G. E., Eccles, K. S., Morrison, R. E., Ford, A., Lawrence, S. E., & Maguire, A. R. (2013). Investigation of steric and electronic effects in the copper-catalysed asymmetric oxidation of sulfides. Tetrahedron, 69(47), 10168-10184. doi:10.1016/j.tet.2013.08.063
  33. O’Mahony, M. A., Croker, D. M., Rasmuson, A. C., Veesler, S., & Hodnett, B. K. (2013). Measuring the Solubility of a Quickly Transforming Metastable Polymorph of Carbamazepine. Organic Process Research & Development, 17(3), 512-518. doi:10.1021/op300228g
  34. O’Mahony, M. A., Seaton, C. C., Croker, D. M., Veesler, S., Rasmuson, A. C., & Hodnett, B. K. (2013). Investigation into the Mechanism of Solution-Mediated Transformation from FI to FIII Carbamazepine: The Role of Dissolution and the Interaction between Polymorph Surfaces. Crystal Growth & Design, 13(5), 1861-1871. doi:10.1021/cg301456m
  35. O’Neill, M. J., O’Mahony, A. M., Byrne, C., Darcy, R., & O’Driscoll, C. M. (2013). Gastrointestinal gene delivery by cyclodextrins – In vitro quantification of extracellular barriers. International Journal of Pharmaceutics, 456(2), 390-399. doi:10.1016/j.ijpharm.2013.08.073
  36. Orozco, A. M., Al-Muhtaseb, A. H., Rooney, D., Walker, G. M., & Ahmad, M. N. M. (2013). Hydrolysis characteristics and kinetics of waste hay biomass as a potential energy crop for fermentable sugars production using autoclave parr reactor system. Industrial Crops and Products, 44, 1-10. doi:10.1016/j.indcrop.2012.10.018
  37. Orozco, A. M., Al-Muhtaseb, A. H., Rooney, D., Walker, G. M., Aiouache, F., & Ahmad, M. (2013). Fermentable sugars recovery from lignocellulosic waste-newspaper by catalytic hydrolysis. Environmental Technology, 34(22), 3017-3028. doi:10.1080/09593330.2013.798002
  38. Paluch, K. J., McCabe, T., Muller-Bunz, H., Corrigan, O. I., Healy, A. M., & Tajber, L. (2013). Formation and Physicochemical Properties of Crystalline and Amorphous Salts with Different Stoichiometries Formed between Ciprofloxacin and Succinic Acid. Molecular Pharmaceutics, 10(10), 3640-3654. doi:10.1021/mp400127r
  39. Paluch, K. J., Tajber, L., Corrigan, O. I., & Healy, A. M. (2013). Impact of Alternative Solid State Forms and Specific Surface Area of High-Dose, Hydrophilic Active Pharmaceutical Ingredients on Tabletability. Molecular Pharmaceutics, 10(10), 3628-3639. doi:10.1021/mp400124z
  40. Rahme, K., Nolan, M. T., Doody, T., McGlacken, G. P., Morris, M. A., O’Driscoll, C., & Holmes, J. D. (2013). Highly stable PEGylated gold nanoparticles in water: applications in biology and catalysis. Rsc Advances, 3(43), 21016-21024. doi:10.1039/c3ra41873a
  41. Ryan, S. M., McMorrow, J., Umerska, A., Patel, H. B., Kornerup, K. N., Tajber, L., . . . Brayden, D. J. (2013). An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis. Journal of Controlled Release, 167(2), 120-129. doi:10.1016/j.jconrel.2013.01.027
  42. Slattery, C. N., Deasy, R. E., Maguire, A. R., Kopach, M. E., Singh, U. K., Argentine, M. D., . . . Moynihan, H. (2013). Telescoped Approach to Aryl Hydroxymethylation in the Synthesis of a Key Pharmaceutical Intermediate. Journal of Organic Chemistry, 78(12), 5955-5963. doi:10.1021/jo400647t
  43. Slattery, C. N., O’Keeffe, S., & Maguire, A. R. (2013). Electronic effects of aryl-substituted bis(oxazoline) ligands on the outcome of asymmetric copper-catalysed C-H insertion and aromatic addition reactions. Tetrahedron-Asymmetry, 24(20), 1265-1275. doi:10.1016/j.tetasy.2013.09.009
  44. Su, W. Y., Hao, H. X., Glennon, B., & Barrett, M. (2013). Spontaneous Polymorphic Nucleation of D-Mannitol in Aqueous Solution Monitored with Raman Spectroscopy and FBRM. Crystal Growth & Design, 13(12), 5179-5187. doi:10.1021/cg400304c
  45. Tewes, F., Ehrhardt, C., & Healy, A. M. (2014). Superparamagnetic iron oxide nanoparticles (SPIONs)-loaded Trojan microparticles for targeted aerosol delivery to the lung. European Journal of Pharmaceutics and Biopharmaceutics, 86(1), 98-104. doi:10.1016/j.ejpb.2013.09.004
  46. Tewes, F., Paluch, K. J., Tajber, L., Gulati, K., Kalantri, D., Ehrhardt, C., & Healy, A. M. (2013). Steroid/mucokinetic hybrid nanoporous microparticles for pulmonary drug delivery. European Journal of Pharmaceutics and Biopharmaceutics, 85(3), 604-613. doi:10.1016/j.ejpb.2013.03.020
  47. Villari, V., Mazzaglia, A., Darcy, R., O’Driscoll, C. M., & Micali, N. (2013). Nanostructures of Cationic Amphiphilic Cyclodextrin Complexes with DNA. Biomacromolecules, 14(3), 811-817. doi:10.1021/bm3018609
  48. Walker, G. M., McEleney, P., Al-Muhtaseb, A. H., & Bell, S. E. J. (2013). Liquid marble granulation using super-hydrophobic powders. Chemical Engineering Journal, 228, 984-992. doi:10.1016/j.cej.2013.05.055
  49. Walsh, D., McCarthy, J., O’Driscoll, C., & Melgar, S. (2013). Pattern recognition receptors-Molecular orchestrators of inflammation in inflammatory bowel disease. Cytokine & Growth Factor Reviews, 24(2), 91-104. doi:10.1016/j.cytogfr.2012.09.003
  50. Wojnarowska, Z., Grzybowska, K., Hawelek, L., Dulski, M., Wrzalik, R., Gruszka, I., . . . Markowski, J. (2013). Molecular Dynamics, Physical Stability and Solubility Advantage from Amorphous Indapamide Drug. Molecular Pharmaceutics, 10(10), 3612-3627. doi:10.1021/mp400116q
  51. Wojnarowska, Z., Kolodziejczyk, K., Paluch, K. J., Tajber, L., Grzybowska, K., Ngai, K. L., & Paluch, M. (2013). Decoupling of conductivity relaxation from structural relaxation in protic ionic liquids and general properties. Physical Chemistry Chemical Physics, 15(23), 9205-9211. doi:10.1039/c3cp50627d
  52. Yang, H. Y., & Rasmuson, A. C. (2013). Nucleation of Butyl Paraben in Different Solvents. Crystal Growth & Design, 13(10), 4226-4238. doi:10.1021/cg400177u

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